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It is known that the acute HPA response to stress plays an important role and has numerous functions which promote cells survival, but chronic activation of this axis by stressful episodes may lead to a wide range of pathological conditions, including depression

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Researchers at Weill Cornell Medical College, the Icahn School of Medicine at Mount Sinai, Duke University and the Karolinska Institute in Stockholm, Sweden, also contributed to the work

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In some cases, diagnostic testing such as upper gastrointestinal imaging or gastric emptying studies may be appropriate to assess gastric function