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A pooled analysis of the STEP 1-3 trials (n=2,117 semaglutide 2.4 mg, n=1,262 placebo) reported GI adverse events in 72.9% of the semaglutide group versus 47.1% of placebo, with nausea (43.9% vs 16.1%), diarrhea (29.7% vs 15.9%), vomiting (24.5% vs 6.3%), and constipation (24.2% vs 11.1%) the most common categories

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Jastreboff of the Yale Obesity Research Center, explains what was happening inside her body

Gene Ontology (GO) and the Kyoto Encyclopedia of Genes and Genomes (KEGG) were used to evaluate pathways