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Similarly, lack of LC effect has been reported in obese women [42]

17 18 In addition, cell studies indicate Alzheimers disease may be linked with lower DNA methylation, 19 and mitochondrial dysfunction is widely considered an important driver in Alzheimers disease development

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In animal models, even short bouts of voluntary wheel running, ranging from a few hours to several days, can rapidly elevate BDNF expression in the hippocampus

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