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Common incretin-related effects discussed in the broader GLP-1 and metabolic drug class may include gastrointestinal symptoms such as nausea, vomiting, diarrhea, constipation, or abdominal discomfort, but trial observations do not establish safe personal use of a research peptide

Follow-up Re-check IGF-1 and metabolic markers after 6-8 weeks or after meaningful protocol changes

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Oral treatments may expand access further after the FDA approved Novo Nordisks once-daily Wegovy pill in December 2025, with launch planned for early 2026