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Additionally, the vascular endothelium (the inner lining of the blood vessels) requires significant energy to produce nitric oxide, a molecule essential for regulating blood vessel dilation and constriction

In addition to the regulation of 1 C metabolism, emerging evidence shows that enzymes in the one-carbon metabolic network also have important non-canonical functions, commonly referred to as moonlighting functions [5]

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Cureus 16, e69418

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