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The microneedling overcomes the topical delivery challenge that the review identifies getting GHK-Cu to the dermal papilla cells identified by the gene data as key targets

Thats not a reason to avoid it, but it is a reason to use it with a vet in the loop, start with conservative dosing, and monitor your dogs response throughout the protocol

Dull skin or skin prone to tightness after cleansing often struggles to find a cleanser that purifies without stripping the skin's barrier