Immunoprecipitates were digested by Lys-C endopeptidase and analysed by direct nano-flow LCMS/MS
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The CB1 receptor antagonist AM251 inhibited the exacerbation of hyperpermeability induced by the two endocannabinoids
Across all six studies, the safety findings were consistent: no serious adverse events, no immunogenic responses, no changes in IGF-1, no glucose or insulin disruption
Image Credit: VectorMine / Shutterstock In a recent review published in the British Journal of Pharmacology , the authors reviewed how glucagon-like peptide 1 receptor (GLP-1) agonists may reduce alcohol and drug-seeking behaviors and evaluated their potential as treatments for addictive disorders
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