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The UK CPRD data were linked to the Hospital Episode Statistics Admitted Patient Care (HES APC) and the Office for National Statistics (ONS) databases, but the linkage was available only in a subset of individuals

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Patients exhibit abnormal GAA trinucleotide repeat expansions in the first intron of the frataxin gene on chromosome 9q, leading to frataxin deficiency [105, 106]

This normalization can result in improved sleep quality, mood stabilization, and enhanced cognitive function Anisimov et al., Neuroendocrinol Lett , 2001

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