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Interestingly, both in vitro and in vivo work on rodents demonstrated that GLP-1RAs can affect growth-related phenotypes by modulating osteoblast physiology [8], [9]

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Key Industry Developments: In October 2025 , Eli Lilly and Company achieved its fourth Phase III success with its oral GLP-1 receptor agonist, orforglipron, in type 2 diabetes trials

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