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Free radicals, characterized by one or more unpaired electrons, exhibit high reactivity, and their generation in biological systems predominantly involves oxygen and nitrogen species, including hydrogen peroxide (HO), organic hydroperoxides, nitric oxide, superoxide, and hydroxyl radicals 45

Other studies reported lactic acidosis and increased alanine levels, it is highly recognized that high concentrations of lactate can inhibit mitochondrial respiration and disbalance the redox equilibrium (Oliveira et al., 2005)

This typically affects people who are overweight or who have insulin resistance such as diabetes patients

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