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demonstrated that baicalin, a major component of Scutellaria, prevents ferroptosis damage in transient middle cerebral artery occlusion (tMCAO) mice or OGD/R cells by enhancing GPX4 expression (Li M

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Using site-directed mutagenesis-based biochemical assays, we further validated the specific interactions between RNF213 RING and IpaH1.4 LRR found in the complex structure