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The real-time quantitative PCR The expression of the anti-apoptotic gene Bcl-2 was significantly downregulated in the GLP group compared to the control group (0.43 0.16 vs

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doi:10.3389/fnins.2016.00564 36

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Incretins can also mobilize stored Ca 2+ in intracellular organelles by activating ryanodine (RYR) [8] and inositol 1, 4, 5-trisphosphate receptors (IP 3 R) [9]