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Integrating these exercise strategies with nutritional support is essential to preserve muscle mass, reduce fatigue, and maximize the benefits of GLP-1RA therapy ( Table 1 Physical activity recommendations in people with obesity on GLP-1RAs

The evidence base is thin compared to pharmaceutical options

Knowing how hormones affect weight can establish realistic expectations for those looking into retatrutide, particularly when weight is being held on by post-pregnancy hormone shifts

Weight loss maintenance is a key concern for many individuals

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