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HELPS ATTENUATE MUSCLE FATIGUE: It is a well-established fact that contracting skeletal muscles produce free radicals and the increased production of reactive oxygen species is linked with muscle fatigue

This tripeptide is most concentrated in the liver, where it binds toxins and metabolic byproducts so they can be safely removed

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Integration of local IGF-I/IGF-IR signaling with systemic hormones Integration with GH Although it is well established that GH stimulates hepatic gene expression to make and supply IGF-I to the circulation, recent studies suggest that changes in circulating IGF-I levels may be an indicator of GH status, but may not be directly involved in controlling local functions in non-hepatic tissues, including bone (68)

doi: 10.1016/j.redox.2023.102840