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Although vitamin B12 deficiencies are rare in the U.S., certain medications and health conditions such as pernicious anemia can affect the absorption of vitamin B12 and contribute to a deficiency

[11] Bile-acid sequestrants and orlistat impair intestinal absorption of fat-soluble vitamins, explaining why some patients switch to parenteral therapy, whereas magnesium-containing antacids and digoxin can synergise with vitamin D to provoke hypermagnesaemia or digitalis toxicity if calcium rises unchecked

Improving insulin sensitivity can also help manage high blood pressure, reducing the risk of heart disease

It's a hard line

When ingested, it is the same toxin that causes botulism, a form of food poisoning