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However, the lack of universal synergy in all contexts indicates that the specific polyphenol, the exercise modality, and the target physiological outcome are critical determinants of the presence and magnitude of synergistic effects, necessitating precise research designs for future investigations (87, 88)

1,23,24,25 In this article, we review the complex physiological roles and metabolism of uric acid and the interconnections of mechanisms between hyperuricemia and potential diseases

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