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Diabetes should be well-managed before starting therapy Active pituitary tumors: Stimulating a gland with an active tumor is contraindicated Monitoring Requirements Safe use of CJC-1295/Ipamorelin requires ongoing physician monitoring: Baseline labs: IGF-1, fasting glucose, HbA1c, thorough metabolic panel, CBC 4-6 week follow-up: IGF-1 to confirm dose response

The mean decline in eGFR at 5 years compared to baseline did not significantly differ between groups (KIGS, 5.8 ml/min/1.73 m 2

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