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It is noteworthy that while multiple drug concentrations may be designed in other studies, for our study, minimizing the drug dose while achieving its effect was considered for safety reasons, given that PE is a pregnancy-related disease, and medication use during pregnancy is restricted

In uveal melanoma, it has been demonstrated that lactate supplementation to in vitro cultured cells increases the mRNA expression of factors involved in mitochondria biogenesis and activity, suggesting a metabolic shift towards an oxidative metabolism [32]

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