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B 0 is the baseline motor score, E max is the maximum inhibitory effect, Cp is the apomorphine plasma concentration predicted by the PK model, Ce is the drug concentration at the site of action, EC 50 is the drug concentration that causes 50% of the maximum effect, g is the Hills sigmoid coefficient, and k e0 is the first-order plasma-effect-site equilibration rate constant
By contrast, CIBB treatment in the CI-M group significantly reduced the percentage of M1 macrophages (31.81% in the CI-M group) and increased the percentage of M2 macrophages (26.18% in the CI-M group) close to that in the control group
Navarro SL, Chang J-L, Peterson S, Chen C, King IB, Schwarz Y, et al
Application as an adjunct to IVF or other fertility treatments is conceivable, for example, as topical treatment to enhance endometrial lining or shield gametes during manipulation
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