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The rapid symptom improvement described in a BN case report using liraglutide, with remission occurring within two weeks and maintained for five years [57], may compatible with a possible replacement-like mechanism, although this interpretation remains speculative and requires confirmation in controlled studies

Obesity Reviews , 24(3), e13456

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Therefore, without H 2 O 2 , the drug release rate of PEG-T ECM -NS at pH 6.8 was only about 28% and slightly faster that under physiological condition (about 23%)

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