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falciparum standard in vitro culture conditions were conducted as previously described ( Eryptosis Assay and Flow Cytometry Analysis Previously described eryptosis inducers were selected for this study based on their use (or potential use) in the clinic, their known targets and/or their previously described antimalarial activity ( Table 1 ): amiodarone HCl (Selleck Chem, #S1979), apigenin (Selleck Chem, #S2262), BAY 43-9006 (AdipoGen Life Sciences, #AG-CR1-0025), benzethonium chloride (Selleck Chem, #S4162), cordycepin (Cayman Chemicals, #14426), ionomycin (ThermoFisher, #I24222) and oridonin (Selleck Chem, #S2335)

Biochem Int 16(5):869878 Livardjani F, Ledig M, Kopp P, Dahlet M, Leroy M, Jaeger A (1991) Lung and blood superoxide dismutase activity in mercury vapor exposed rats: effect of N-acetylcysteine treatment

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Cn serum cao cp c gi t 1.300.000 n 7.000.000 ng, thm ch c loi ln n 10.000.000 ng

In the long run, these ROS-mediated effects might influence the rheological properties of erythrocytes, thereby demonstrating the clinical relevance of eryptosis research [118]