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Davies said several GLP-1/glucagon dual agonists have moved on to phase 2 or phase 3 trials, including survodutide (Boehringer Ingelheim), efinopegdutide (Hanmi Pharmaceutical), mazdutide (Eli Lilly and Innovent) and pemvidutide (Altimmune)

Histological scores were determined in a blinded manner by two independent investigators based on the sum of the epithelium and infiltration scores

Trimethylamine N-oxide mediated Y-box binding protein-1 nuclear translocation promotes cell cycle progression by directly downregulating Gadd45a expression in a cellular model of chronic kidney disease

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