GLP-1s offer significant promise to millions of Americans living with obesity, diabetes and/or cardiovascular disease, but their unprecedented demand and high price tags are creating challenging downstream impacts, including fluctuating supply, inconsistent clinical support, and runaway cost trajectory, said an Evernorth statement
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A new peer-reviewed study from Truveta Research found that while biosimilar adoption increased following formulary changes, 1 in 7 patients switched back to originator adalimumab (Humira) after starting a biosimilar
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Considerations are based on IGF-1 biology, including its influence on growth factor signaling and metabolic regulation