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Obesity is also a leading driver of gastrointestinal (GI) and hepatobiliary cancers, from colorectal cancer to hepatocellular carcinoma, making any therapy that modifies obesity-related cancer risk directly relevant to gastroenterology practice

The starting dose of semaglutide is 0.25 mg subcutaneous once weekly, which can be increased incrementally every four weeks to a maintenance dose of 2.4 mg: 250 weeks 14: 0.25 mg weeks 58: 0.5 mg weeks 912: 1 mg weeks 1316: 1.7 mg maintenance dose: 2.4 mg

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That logjam is a real constraint, but necessity is the mother of ingenuity and will likely be solved