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This glucagon-like peptide-1 receptor agonist (GLP-1 RA), developed by Novo Nordisk, has undergone extensive investigation through multiple clinical trial programs

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This was a retrospective study that included 4,144 people with obesity who were prescribed liraglutide, 613 prescribed semaglutide, and 654 prescribed the older treatment

In addition, in a different group of rats, BDNF levels measured by ELISA on a tissue punch of the dDG infected with LV-shBDNF were reduced by 52.29%2.37 relative to controls (Figure 1c)