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The long-term implications of treating developing individuals with potent metabolic modulators remain uncertain, creating both clinical need and regulatory complexity for companies considering pediatric development programs

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Food Chem Toxicol 42(12):19371947 Herman-Antosiewicz A, Singh SV (2005) Checkpoint kinase 1 regulates diallyl trisulfide-induced mitotic arrest in human prostate cancer cells

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Exendin-4 increases bone mineral density in type 2 diabetic OLETF rats potentially through the down-regulation of SOST/sclerostin in osteocytes