glp 1 agonists reduce inflammation Mechanisms by which GLP-1 may exert beneficial effects on the Comprehensive mechanistic diagram showing GLP-1

Directly protects endothelial walls using profound nitric oxide (NO) generation

Przypisuje si mu funkcj w detoksykacji organizmu - reaguje on z wolnymi rodnikami i wspiera regeneracj uszkodzonych czsteczek

2012;97(3):E41922

J Eur Acad Dermatol Venereol (2014) 28(s5):1726

A refined definition of astrocyte reactivity includes four key features: (1) cellular, molecular and functional changes in response to CNS insults, (2) graded responses depending on insult severity, (3) context-dependent reactions influenced by intra- and intercellular signaling and (4) beneficial or detrimental effects on surrounding cells 35