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Further, the study of L-ASNase/combinatorial therapies with other anticancer drugs is a promising therapeutic means for resistant cancers, and the synergistic effect of L-ASNase together with chemotherapy, targeted therapy and immunotherapy has been proven

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They argued that a pharmacy cannot compound its way around basic uncertainty about identity, effectiveness, dosing, and long-term safety

Structurally, AOD 9604 retains a disulfide-linked cyclic conformation formed by cysteine residues, preserving key features of the native GH region responsible for lipid metabolism signaling