More recent preclinical work has examined GHK-Cu in rodent models of pulmonary fibrosis, silicosis and airway remodelling, with oxidative stress and inflammatory signalling as the reported endpoints
Michalczyk K, Cymbaluk-Poska A
For example, we found the half-lives of free 4-hydroxyproline in the blood of 8- and 160-day-old pigs are 46.2 2.8 and 60.5 3.3 min (mean SEM, n = 6), respectively, as determined by intravenous administration of 4-hydroxyproline (50 mg/kg BW) and the single exponential model of its pharmacokinetics (Wu et al
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Dosing applicator a dosing format intended for research use, enabling standardised dispensing of the reagent within laboratory procedures (RUO)