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Additionally, GLP-1 therapy may increase serum uric acid levels through weight loss-related purine metabolism shifts, further elevating nephrolithiasis risk in susceptible individuals

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Data analysed by one-way ANOVA, multiple comparison, Bonferroni post hoc test ( c , e , g , l , n , p , v , x and z ) and two-way repeated measures ANOVA to assess main effects of treatment ( i , j , q , s and t )