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Since many diseases are localized, delivery of a medication to the disease site serves well for the purpose of disease treatment

doi:10.1016/j.biopha.2018.10.133 46

These complexes not only alter the physicochemical properties of curcumin but also affect the biological reactivity of the metals involved [33,34]

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It binds to insulin which then initiates a cascading pathway of metabolic events through the action of the enzyme phosphatidylinositol-3-kinase and the activation of insulin-1 receptor substrate