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Mitochondrial impairment further results in elevated production of ROS, exacerbating oxidative stress in the placental environment

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AlphaFold structures for all relevant SLC25 proteins were obtained in the conformational state open to the cytoplasm and intermembrane space (C-state) except for SLC25A39 and SLC25A40 whose predicted structures are in the M-state, open to the mitochondrial matrix

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