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In 2025, KFF reported that 19% of employers with 200+ workers and 43% with 5,000+ workers covered GLP-1s for weight loss, and employers are expected to revisit coverage and cost-containment strategies each year as demand remains high

Early research suggests that 5-Amino-1MQ works by reducing the activity of NNMT (nicotinamide N-methyltransferase), a naturally occurring enzyme found throughout the body that plays a crucial role in regulating cellular energy metabolism and fat storage within cells, as well as the rate at which your body burns through NAD+

In an interview with HCPLive, Mark Taylor, MD, consultant psychiatrist at The Edinburgh Practice and professor at Griffith University, discussed a Swedish registry study that compared periods when patients were on GLP-1 therapy versus off treatment, effectively using each patient as their own control

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The study was restricted to patients who had no history of antidepressant use to reduce any confounding by centrally acting agents