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Halaris A, Myint AM, Savant V, Meresh E, Lim E, Guillemin G, et al

A phase 2 trial (NCT03659682), with Semaglutide (a more potent GLP-1 RA), not yet recruiting, is designed to assess the effects of once-weekly subcutaneous semaglutide (1 mg) on motor symptoms (MDS-UPDRS III in the OFF state), DAT-SPECT imaging, cognition, and non-motor symptoms over 48 months [39]

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2024;6(4):fcae258

This is particularly important for older adults, who are at greater risk of sarcopenia, and for individuals aiming to maintain physical function and metabolic health during treatment