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Another limitation is that the final study sample was determined by specific time constraints due to COVID-19 restrictions, which undoubtedly had an impact on the small sample size
, 16 have reported mean CAL values of 2.9 mm for e-cigarette users, 2.2 mm for non-smokers, and 3.5 mm for smokers, these findings should be interpreted with caution due to potential confounding factors, including lack of comment on prior smoking history and limitations in cross-sectional design of the study
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