soul trial oral semaglutide cardiovascular outcomes 2024 nejm PDF) and in People With Type 2 Diabetes, According to SGLT2i Use: Prespecified Analyses of the Randomized FLOWing with the SemagluTIDE —

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TL;DR Mounjaro delivers 20.2% average body weight loss versus Wegovys 13.7% in the landmark SURMOUNT-5 head-to-head trial However, Wegovy costs less ($599.95/month cash vs $559.99 $799.99/month for Mounjaro) and is approved for cardiovascular disease risk reduction Mounjaro is a dual GIP/GLP 1 receptor agonist while Wegovy is GLP 1 only Both are prescription only medications requiring weekly injections with similar gastrointestinal side effects Choose Mounjaro for greater weight loss

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10.1016/j.soard.2017.01.047 Surg Obes Relat Dis