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Many clients notice improvements in energy and focus within days, though results vary

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Kay EJ, Paterson K, Riera-Domingo C, Sumpton D,Dbritz JHM,Tardito S, Boldrini C, Hernandez-Fernaud JR, Athineos D, Dhayade S,Stepanova E,Gjerga E,Neilson LJ,Lilla S,Hedley A,Koulouras G,McGregor G,Jamieson C,Johnson RM,Park M,Kirschner K,Miller C,Kamphorst JJ, Loayza-Puch F, Saez-Rodriguez J

We administered 75 mg/kg caffeine and 100 mg/kg EGCG to observe the commonality and specificity of the two treatments in an HFHC-induced mouse model of NASH

These include reduced microbial diversity, decreased abundance of beneficial taxa such as Bifidobacterium and Faecalibacterium prausnitzii , and increased representation of pro-inflammatory microbes (Khavandegar et al., 2024