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Search strategy and inclusion criteria This mini-review was based on a targeted literature search conducted in PubMed/MEDLINE and Scopus from January 2015 to August 2025, using the keywords GLP-1 receptor agonists, exercise, physical activity, obesity, type 2 diabetes, and weight loss. Additional terms ( lean mass, body composition, insulin sensitivity, cardiometabolic, combined intervention ) were used in secondary searches

23, 24 We have therefore evaluated GLP1R in human thyroid and pancreas tissues using an extensively validated GLP1R monoclonal antibody 24 that we used for immunohistochemistry and western blots and that we compared with results of GLP1R autoradiography in the same tissues

Gut 58 , 220227 (2009)

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Images were captured by microscopy (ECLIPSE Ci-L, Nikon, Tokyo, Japan)