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The presence of translation-inhibiting secondary structures within the 5 UTR of mRNA transcripts has been previously demonstrated [82, 86], and designing ASOs that are complementary to these regions, could potentially relieve translational inhibition (Fig

Hyperpigmentation: Retinol can fade dark spots and even out skin tone

balances MMP/TIMP for non-fibrotic ECM turnover

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Some common endotypes of these diseases, with similar presentations but differing etiologies, include cystic fibrosis (CF), chronic obstructive pulmonary disease (COPD), primary ciliary dyskinesia (PCD), and non-CF bronchiectasis (NCFB)