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Loss of Lean Mass Weight loss, achieved through a calorie-reduced diet, which may or may not involve the use of GLP-1 agonist drugs, decreases both fat and lean body mass

Both medications have shown significant results for controlling blood sugar levels in people with type 2 diabetes and weight loss for people with obesity or overweight

European Journal of Vascular and Endovascular Surgery, 31 (1), 111

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The index date was defined as the date of first recorded use of tirzepatide for the tirzepatide group, and the date of HFpEF diagnosis for the control group