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Cost-effectiveness analyses consistently show that drug treatment becomes economically attractive only in patients with at least stage F2 fibrosis or with high cardiovascular risk, whereas lifestyle modification and, in particular, physical activity that induces exercise-mediated anti-inflammatory effects and dietary changes are the preferred first-line options for early, uncomplicated disease [4547]

Studies have found that supplementing with chondroitin supports healthy inflammation response as well as cardiovascular health, bone health, skin health and healthy cholesterol levels

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"NIH Launches Large Clinical Trial on EDTA Chelation Therapy for Coronary Artery Disease"