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One of the consequences of chronically increased ductal replication can be distortion of small pancreatic ducts with subsequent outflow obstruction of pancreatic enzymes providing a plausible mechanistic link between obesity and/or diabetes and the increased risk for pancreatitis

References Menezo, Y., Clement, P., Clement, A., & Elder, K

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TB-500 operates through actin regulation, cellular migration enhancement, and anti-inflammatory cytokine modulation

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