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Similarly, patent holders, like Novo Nordisk, do not hold a patent on the ingredients contained in an FDA-approved therapy, only the FDA-approved medication itself

"A Trial Comparing the Safety and Efficacy of Semaglutide Once Weekly Versus Sitagliptin Once Daily in Japanese Subjects With Type 2 Diabetes (SUSTAIN)"

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Pregnancy or breastfeeding: Semaglutide can not be used during pregnancy or breastfeeding, as its effects on the fetus and infants are not fully known

In August 2025, Judge Karen Spencer Marston instructed plaintiffs to support gastroparesis allegations with objective gastric emptying tests