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Higher risk groups include women, people over 40, those who lose weight very quickly, and those with a personal or family history of gallbladder disease

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Seven to nine hours of quality sleep per night supports the metabolic environment that allows tirzepatide to work optimally

The STEP 8 trial (published in JAMA, 2022) enrolled 338 adults with overweight or obesity, without type 2 diabetes, and randomised them to receive either semaglutide 2.4 mg weekly or liraglutide 3.0 mg daily for 68 weeks

Serious hypersensitivity reactions including anaphylaxis and angioedema have been reported with Ozempic