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The mice were divided into three groups and treated with tail vein injections of either saline (Saline), scExe4 donor plasmid loaded LNP alone (Donor), or scExe4 donor plasmid loaded LNP plus Cas9 plasmid loaded LNP (Donor+Cas9)

The authors identified BPC-157 as having significant potential and described it as a feasible therapy candidate for conservative treatment of hypovascular and hypocellular soft tissues such as tendon and ligaments, following further development

Much like any new medication application, FDA approval will be needed before widespread adoption can safely occur

- Dosage: 200 mcg to 300 mcg per day, typically divided into two doses (morning and evening)

doi:10.1073/pnas.85.19.7293