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Nat Rev Endocrinol 8(12):728742 Davies MJ, Bain SC, Atkin SL, Rossing P, Scott D, Shamkhalova MS et al (2015) Efficacy and safety of liraglutide versus placebo as add-on to glucose-lowering therapy in patients with type 2 diabetes and moderate renal impairment (LIRA-RENAL): a randomized clinical trial

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Programs that treat GLP-1 therapy as 'take this injection weekly and lose weight automatically' set patients up for the two-thirds rebound rate documented in post-discontinuation studies