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At least one study showed that an acute injection of trimetazidine (10 mg/kg) reduced hippocampal inflammation measured by TNF- and IL-1 while protecting against seizure and associated cognitive impairments in diabetic and epileptic rats [161]

Biol Trace Elem Res 2022;200(4):1580-1590

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A Newly Synthesized Flavone from Luteolin Escapes from COMT-Catalyzed Methylation and Inhibits Lipopolysaccharide-Induced Inflammation in RAW264.7 Macrophages via JNK, p38 and NF-B Signaling Pathways

If cost is a concern, adjust your reconstitution volume so the vial is used up within 28 days at your current dose level rather than stretching an old vial