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[PubMed: 8528260] 20

In contrast, what happens to GABA A and glycine signaling remains controversial: global measurements of the number of inhibitory interneurons, GABA levels, its synthesis enzyme glutamate acid decarboxylase (GAD) or its vesicular transporter (VGAT) as well as GABA A receptors (GABA A Rs) yield contradictory results 8,9,10,11,12,13,14,15,16,17,18

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Initially, these phagocytes adopt a pro-inflammatory, microbicidal program characterized by elevated production of reactive oxygen species (ROS), nitric oxide (NO), proteolytic enzymes, and pro-inflammatory cytokines like IL-1, IL-6, and TNF-, enabling efficient pathogen clearance [39]