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Additionally, beta glucan molecules differ in structure from species to species, a significant factor in determining their bioactivity

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(C) 2+ -dependent EV biogenesis and cargo sorting, enriching pro-metastatic proteins (e.g., MMP2/MMP9) and altering miRNA profiles (upregulate oncogenic miR-155/-21/-210 and suppress tumor-suppressive miR-126/-200c)

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2f), was found to be much less permissive than for V12 and F112 (Fig