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However, certain conditions, such as digestive disorders, can interfere with the absorption of B12

Too much folate can cause nausea, loss of appetite, confusion, irritability, and changes in sleep

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Vitamin D injections : Therapeutic doses vary but often include amounts like 50,000 IU for treating deficiencies

The B12 component can help with the low-energy stretch that fall and winter bring for some people, which makes it easier to stay active